Thursday, 31 March 2022

A case of fever ,oral ulcer,joint pain

 

K.sannith reddy 

Roll no:55

30 year old female patient came to OPD with chief complaints of fever, rashes , joint paints.

History of present illness
Patient apparently asymptomatic 2 years ago then she developed  fever, rashes , joint pains 
 Then she went to local hospital where they had given  some antibiotics and pain killers
   
Symptoms  subsided and recurred after some time
She continued  to take this medication but symptoms were going to reccur
 Lastly she went to private hospital  there she diagnosed her as systemic lupus erythamatosis

 It was diagnosed by renal biopsy and ANA profile 
 Which was 
  • Anti -RNP/ Sm and Anti- Sm, Anti-Jo 1, Anti - ds DNA, nucleosomes and RIBOSOMAL P- PROTEIN
  • Biposy showed focal mild increased endocapillary cellularity pointing towards FOCAL GLOMERULONEPHRITIS
  • Proteinuria  and increased creatinine.                
She has history of  hair loss

Initially 3 days of her treatment after diagnoses she developed facial puffiness blurring of vision the 
She had on treatment
 
 She was put on Tab. OMNOCORTIL 50 mg for 3 days and steroid injections and was tapered over 6 months to 2.5mg. and she is taking hydroxy chloroquine along with this 


After 6 months, steroids were stopped and was started on

  •  Tab. MFM (2 tab at 8 AM and 1 tab at 8 PM), after that she had symptoms for which they added methotrexate to  it  after few weeks.
  • IN FEBRUARY 2021, She was started on METHOTREXATE  after which she noticed increase in number of oral ulcers , so she went to a private hospital 15 days later, and was started again  on OMNOCORTIL 5mg
  • She later developed blurring of vision more in day light, for which she was diagnosed with cataract in her left eye.
After that she stopped steroid usage but she is on MFM and HCQS till this  day

 After that she lost vision on both eyes and under went cataract surgery on Feb 12 
 From last 6 months she is having mouth ulcers on and off 
 But from last 7 days she is having increased symptoms of ulcers joint pains fever such that
She is not able swallow foods  with this history she came to this hospital .

Past history : 

Patient is a known case of HYPOTHYROIDISM since and is on Thyronorm 50mcg .
Not a known case of DM, HTN, EPILEPSY, TB, BRONCHIAL ASTHMA

PERSONAL HISTORY:

DIET- mixed
Appetite: Normal
Bowel and bladder movements are normal
Sleep: Adequate
No known addictions and allergies.

Menstrual History:
She bleeds for 3 days in a 30 day cycle 
She uses 3 pads per day.
Recently, she complains of spotting 5 days before her first day of menses ( oligomenorrhea)

Marital history:

In 2014 Dec, when she was 24 years she was a married. 

Antenatal history:
P3 L2 A1
In 2015, her first pregnancy reached full term and NVD was done. 
She developed high grade fever in her 6th month, and was diagnosed with malaria.
She developed severe back and loin pain in her 8th month, and USG was done which showed swollen kidneys for which she was prescribed antibiotics and sent home.

In 2018, her second pregnancy, she suffered an abortion in the 4th month. On investigation, she was found to be suffering from Hypothyroidism and was started on medication. 

In 2019, her third pregnancy, reached full term and NVD was done. 

Family History:
Insignificant

General examination: 

Patient is conscious, coherent and cooperative. 

Vitals on admission: 

Temp: 102°F

BP: 120/80

PR: 110 bpm


CVS: 

On palpation,

-Apex beat felt at 5th intercostal space along midclavicular line

-JVP not raised

-No precordial bulge 

-No parasternal heave

On percussion, the heart borders were in normal limits   

On auscultation, S1, S2 heard; no murmurs


RS: BAE present, NVBS heard 


CNS: E4V5M6

SENSORY EXAMINATION-


Normal sensations felt in all dermatomes


MOTOR EXAMINATION:


Normal bulk in upper and lower limb


Normal tone in upper and lower limb


Normal power in upper and lower limb


Gait is normal


REFLEXES:


Normal, brisk reflexes elicited- biceps, triceps, knee and ankle reflexes elicite



CEREBELLAR FUNCTION:


Normal functions


No meningeal signs were elicited.


P/A: soft, non tender 

Investigations.    

Hemogram: 

Hb: 9.3

TLC: 3500

N/L/E/M: 78/15/2/5

Plt: 2.3


CUE: 

Albumin: trace 

Sugars: nil

Pus cells: 2-3 

Epithelial cells: 2-3 


APTT: 32s

PT: 16s

INR: 1.11



X ray. 










Provisional diagnosis: SYSTEMIC LUPUS ERYTHEMATOSUS - CLASS III LUPE NEPHRITIS
 With hypothyroidism 

INTERNSHIP ASSESSMENT ROLL NO:65

INTERNSHIP ASSESSMENT: Posted in department of GENERAL MEDICINE from 12/12/22 to 11/2/23. UNIT duties—-First 15 days (12/12/22-26/12/22)   L...